灵活使用有限的资源为前额叶皮层的序列工作记忆
Siwei Li1,2, Jingwen Chen1,2, Cong Zhang1
1Institute of Neuroscience, Key Laboratory of Brain Cognition and Brain-Inspired Intelligence Technology, CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai, 200031, China.
Nature communications
|November 24, 2025
概括
大脑通过动态利用神经表征来灵活地分配有限的工作记忆 (WM) 资源. 这种策略平衡了概括和干扰,在能力范围内优化认知表现.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 计算神经科学是一种神经科学.
背景情况:
- 大脑的工作记忆 (WM) 容量是有限的,但它可以将新信息概括为新的信息.
- 管理有限的WM资源合理分配的机制尚未得到充分理解.
研究的目的:
- 研究前额叶皮质如何在序列工作记忆 (SWM) 任务中分配工作记忆资源.
- 阐明在WM中灵活资源利用和概括的基础的神经机制.
主要方法:
- 在执行SWM任务的非人类灵长类动物中利用成像和电生理记录.
- 分析神经表征,包括几何结构和子空间动态,与WM负载相关.
主要成果:
- SWM的神经表示,包括几何和等级子空间,随着WM负载动态变化.
- 通过神经信号强度和调量化的工作记忆资源,在SWM等级之间灵活共享.
- 前额叶皮层采用了不同的神经策略:共享调以实现概括和分离调以尽量减少干扰,实现成本效益的权衡.
结论:
- 构成性的几何是灵活使用有限的工作内存资源的基础.
- 前额叶皮层的神经资源分配动态预测SWM任务中的行为结果.
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