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Updated: Jan 10, 2026

Lensless Fluorescent Microscopy on a Chip
11:23

Lensless Fluorescent Microscopy on a Chip

Published on: August 17, 2011

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利用空间角冗余来实现自主监督的3D光成像无时间依赖的无化

Zhi Lu1,2,3,4,5,6, Wentao Chen3,7, Feihao Sun2,3,4

  • 1Department of Psychological and Cognitive Sciences, Tsinghua University, Beijing, China.

Nature communications
|November 25, 2025
PubMed
概括

光子噪声限制了光成像. 光场消噪 (LF-denoising) 使用空间角冗余来实现高准确度的3D成像,而不会牺牲分辨率,这对于动态生物研究至关重要.

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Super-resolution Fluorescence Microscopy01:37

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Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
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