在一项随机对照试验中,对接受抗血栓治疗的患者进行临床药房服务的评估
Damla Sosyal1,2, Muhammed Yunus Bektay3,4, Nusret Acikgoz5
1Department of Clinical Pharmacy, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.
Scientific reports
|November 25, 2025
概括
临床药剂师在接受抗血栓治疗的心脏病患者中显著减少了与药物相关的问题 (DRPs). 他们在多学科团队中的积极参与改善了药物安全性,并优化了药物治疗.
科学领域:
- 药理学 药理学是指药理学的学科.
- 临床药房 临床药房
- 患者安全 患者安全
背景情况:
- 接受抗血栓治疗的患者由于复杂的药物治疗方案而面临与药物相关问题的风险增加.
- 临床药剂师在优化药物治疗和通过药物审查提高患者安全方面至关重要.
研究的目的:
- 评估临床药房服务对在接受抗血栓药物治疗的住院心脏病患者中识别和预防DRPs的影响.
- 评估结构化药物审查和多学科合作在管理DRP的有效性.
主要方法:
- 这是一项前性随机对照试验,涉及400名接受抗血栓剂治疗的成人心脏病患者.
- 患者被分配到对照组 (没有干预) 或接受临床药剂师主导药物审查的干预组,使用PCNE分类v9.1.1.
- 在病房巡视期间,向医生传达了DRP的建议,并跟踪患者重新入院.
主要成果:
- 在对照组中共发现了561个DRP,在干预组中发现了497个DRP.
- 干预组每位患者临床显著的DRP平均数量明显较低 (p < 0.05).
- 在干预组中,医生接受了对临床显著的DRP提出的266条建议中的94.76%.
结论:
- 积极的临床药剂师参与多学科医院团队显著减少了在抗血栓治疗患者的DRPs.
- 将临床药剂师整合到住院护理中,可以优化药物治疗,并改善药物安全结果.
- 临床药剂师的结构化药物审查在管理复杂患者病例方面是有效的.
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