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Updated: Jan 10, 2026

In Vivo Modeling of the Morbid Human Genome using Danio rerio
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人类疾病遗传学的全蛋白质组模型

Rose Orenbuch1, Courtney A Shearer1, Aaron W Kollasch1

  • 1Department of Systems Biology, Harvard Medical School, Boston, MA, USA.

Nature genetics
|November 25, 2025
PubMed
概括

我们开发了popEVE,这是一种新的深度学习模型,可以准确预测整个人类蛋白质组的遗传变异的影响. 这种工具有助于诊断罕见的遗传疾病,特别是在复杂的情况下.

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