优先考虑灵活的工作记忆表示依赖于在记忆重新激活过程中对海马半岛网络的参与
Chunli Chen1, Yusi Xie1, Jiaxin Zhao1
1The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, University of Electronic Science and Technology of China, Chengdu, China.
Communications biology
|November 25, 2025
概括
工作记忆 (WM) 中的回顾性线索通过重新激活记忆表征来增强注意力,特别是涉及新发现的副海马岛网络. 这个过程对于优化行为和注意力控制至关重要.
科学领域:
- 认知神经科学 认知神经科学
- 神经成像是一种神经成像.
- 工作记忆研究 工作记忆研究
背景情况:
- 工作记忆 (WM) 中的回顾性线索引导注意力,但底层的大规模大脑网络尚未完全理解.
- 面对面的注意力网络受到影响,但更广泛的皮质参与仍然难以捉摸.
研究的目的:
- 识别参与工作记忆中的回顾性暗示的新型大脑子网络.
- 调查动态网络活动及其与WM任务期间行为表现的关系.
主要方法:
- 结合脑电图 (EEG) 源定位与贝叶斯的非负矩阵因子化.
- 分析了动态网络相似性 (DNS) 以映射大脑状态过渡.
- 与行为测量和α波段振荡相关联的网络活动.
主要成果:
- 确定了9个与WM任务相关的子网络,包括两个新型网络:左侧和右侧副海马岛网络 (lPIN和rPIN).
- 与中性线索相比,回溯线索通过lPIN和rPIN诱导了更强的记忆重新激活.
- 编码期间的网络配置和保留期间的散发模式,以lPIN/rPIN作为枢纽,与行为和α横向化有显著的相关性.
结论:
- 副海马岛网络在通过回顾性注意力增强WM行为方面发挥着至关重要的作用.
- 这些发现支持了大规模网络层面上反效应的注意力强化假设.
相关概念视频
Working Memory
774
Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
774
Role of Hippocampus in Memory
1.4K
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
1.4K
Role of Cerebellum and Prefrontal Cortex in Memory
988
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
988
Storage
345
A schema is a mental framework that helps individuals organize and interpret information. Schemata, formed from previous experiences, influence how we process new information: how we encode it, the inferences we make, and how we retrieve it. For instance, a schema for what a typical classroom looks like might include desks, a teacher's desk, a whiteboard, and students in such an environment. This expectation helps us quickly understand and navigate new classrooms without needing to analyze...
345
Chunking and Rehearsal in Sensory Memory
546
Improving short-term memory can be achieved through techniques like chunking and rehearsal. Chunking involves organizing information into larger, more manageable units. This technique is particularly useful for information that exceeds the typical memory span of between five and nine items. For instance, logging into an online account with a password like "ta89vq0179gz" involves grouping letters and numbers into three chunks—ta89, vq01, and 79gz. It makes large amounts of...
546
Higher Mental Functions of Brain: Learning and Memory
1.9K
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
1.9K


