母亲暴露于石油和天然气开采过程与不良出生结果之间的关联:系统性审查和元分析
Ali Mohammad Latifi1, Fatemeh Abdi2, Mohammad Miri3
1Medical Biotechnology, Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.
BMC pregnancy and childbirth
|November 25, 2025
概括
母亲接触石油和天然气污染物与早产,流产的风险增加有关,对于妊娠年龄的婴儿来说更小. 由于研究的局限性,需要进一步的研究来证实这些关联.
科学领域:
- 环境健康 环境健康
- 生殖流行病学 生殖流行病学
- 职业健康 职业健康 职业健康
背景情况:
- 石油和天然气开采对能源和经济至关重要,但与不良妊娠结果有关.
- 本综述探讨了石油和天然气污染物对母亲健康和分娩结果的影响.
研究的目的:
- 系统地审查和元分析母亲暴露于石油和天然气污染物和不良出生结果之间的关系.
- 评估与早产,流产,死产,出生缺陷,怀孕年龄小,低出生体重和出生体重的关联.
主要方法:
- 在五个主要数据库中进行全面的文献搜索,截至2024年6月.
- 包括24项评估母亲暴露于石油和天然气开采过程和出生结果的研究.
- 使用纽卡斯尔-太华尺度和GRADE框架评估研究质量.
主要成果:
- 发现了增加早产 (OR:1.07),流产 (OR:2.03) 和SGA (OR:1.23) 的几率的显著关联.
- 还观察到降低出生体重 (平均差异:-30.36 g).
- 对于死产,出生缺陷或低出生体重没有显著的关联;注意到异质性和潜在偏差.
结论:
- 母亲接触石油和天然气提取过程可能与不良分娩结果有关,如早产,流产和SGA.
- 结果需要谨慎解释,因为方法的变化,潜在的偏差和高异质.
- 建议通过标准化暴露评估和更大的队列进行进一步的研究.
相关概念视频
Teratogenicity
3.9K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
3.9K
Pathophysiology of Diabetes
3.1K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.1K


