凯菲尔对ADHD儿童症状,睡眠和肠道微生物群的影响:一项随机对照试验
Kate Lawrence1, Philippa Fibert2, Miguel Toribio-Mateas3,4
1Faculty of Sport, Technology and Health Sciences, St Mary's University, Twickenham, London, UK. Kate.Lawrence@stmarys.ac.uk.
BMC psychiatry
|November 25, 2025
概括
开补充剂对ADHD症状没有显著影响,但可能会改善ADHD儿童的睡眠质量. 肠道细菌的组成发生了变化,观察到有益物种增加.
科学领域:
- 神经科学是一个神经科学.
- 微生物学 微生物学
- 儿科 儿科 儿科
背景情况:
- 在注意力缺陷/多动性障碍 (ADHD) 中观察到肠道微生物组合的改变.
- 准肠道细菌为ADHD症状管理提供了一个潜在的治疗策略.
研究的目的:
- 为了研究开补充剂对ADHD症状,睡眠,注意力和ADHD儿童肠道微生物群的影响.
- 为了评估每天在六周内摄入的安全性和有效性.
主要方法:
- 一项为期六周的随机,双盲,安慰剂对照试验,涉及8至13岁的英国儿童,患有多动症.
- 参与者每天要么饮用酒,要么服用安慰剂饮料.
- 主要结局:ADHD症状严重程度 (SWAN尺度). 二次结果:肠道微生物群,胃肠道症状,睡眠,注意力和冲动性.
主要成果:
- 酒并没有显著改变ADHD整体症状严重程度.
- 在基线严重程度高的儿童中,观察到一个趋势,即减少了教师评价的ADHD症状,这种趋势在开菲尔组 (p=0.088) 中被观察到.
- 凯菲尔组通过动图 (p=0.04) 显示了更好的睡眠效率 (更少的清醒时间),但报告了更多的睡眠问题 (p=0.02).
- 在酒组中,有益的肠道细菌显著增加,包括Bifidobacterium和Alistipes物种.
- 没有观察到肠道微生物群α或β多样性的显著变化.
结论:
- 补充可以为ADHD儿童的睡眠质量提供适度的好处.
- 研究结果表明,营养干预措施,如,在治疗多动症方面可能发挥作用.
- 需要进一步的研究来探索ADHD的肠-大脑轴,并优化饮食策略.
关键词:
更多关于 ADHD ADHD 的文章动画摄影是一种动画.注意缺陷过度活动障碍注意力缺陷过度活动障碍孩子 孩子 孩子 孩子发酵食品是一种发酵食品.肠-大脑轴 肠-大脑轴克菲尔 (Kefir) 是一种乳制品.微生物组是一个微生物组.微生物群中的微生物群神经发育障碍 神经发育障碍益生菌 益生菌 益生菌随机对照试验是随机对照试验.睡眠 睡眠 睡眠 睡眠更多相关视频
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