个性化实时远程运动对活在癌症治疗后的个体的影响:跨国超级雨随机对照试验 (LION-RCT) 的研究方案
Anouk E Hiensch1, Jana Müller2, Eva M Zopf3,4
1Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, PO Box 85500, Utrecht, GA, 3508, The Netherlands.
Trials
|November 25, 2025
概括
这项研究调查了癌症幸存者经历副作用的实时远程炼. 有针对性的炼计划旨在改善生活质量,并管理疲劳和痛苦等症状.
科学领域:
- 在瘤学瘤学.
- 运动科学 运动科学
- 康复 康复 康复 康复
背景情况:
- 运动改善生活质量 (QoL),并减少癌症幸存者的副作用.
- 监督和定制的运动干预措施显示出更大的效果,但时间和旅行等障碍限制了访问.
- 现场远程练习提供了一个解决方案,通过视频会议提供监督的会议.
研究的目的:
- 评估针对副作用的实时远程练习的 (成本效益).
- 评估QOL的改善和特定的副作用 (疲劳,情绪困扰,身体功能,化疗诱导的周围神经病变[CIPN]).
- 确定将现场远程运动整合到标准癌症随访护理中的可行性.
主要方法:
- 一项跨国随机对照试验 (RCT) 招募了352名患者,他们接受了治疗后的癌症治疗,至少有一种向副作用.
- 参与者被随机分配到一个为期12周的监督实时远程炼计划或等候名单控制.
- 该计划包括一个基本模块和一个针对个体最负担的副作用的特定模块.
主要成果:
- 主要结局包括与健康相关的QoL (HRQoL) 和标准化症状得分,用于最负担的副作用.
- 评估是在多个时间点进行的,直到基线后的36周.
- 该研究将提供关于这种新的运动交付方法 (成本效益) 的数据.
结论:
- 这项RCT将确定针对癌症幸存者进行面向副作用的实时远程炼的 (成本效益).
- 积极的发现可能会导致实时远程运动被纳入标准的癌症幸存者护理中.
- 这种方法有可能扩大癌症患者获得关键的运动支持的机会.
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