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[在渐进性动脉动脉硬化中血管壁剪切指数]

V A Sandrikov¹, A V Gavrilenko^1,2, N N Al-Yousef¹

¹Petrovsky National Research Center of Surgery, Moscow, Russia.

|November 25, 2025

概括

血管壁剪切应力和振荡指数在患有动脉动脉硬化症的患者中进行了评估. 与健康个体相比,动脉样硬化病变的壁切应力和振荡指数显著改变,这表明诊断的潜力.

科学领域:

心血管研究的心血管研究.
医学成像医学成像
生物医学工程生物医学工程

背景情况:

动脉动脉样硬化是脑血管疾病的重要危险因素.
准确评估血管壁机制对于了解疾病进展至关重要.
目前的方法可能无法完全捕捉血液流动和血管壁相互作用的动态变化.

研究的目的:

评估血管壁剪切应力 (WSS) 和振荡指数 (OSI) 在表征动脉动脉样硬化的有用性.
为了比较健康志愿者的WSS和OSI与患有动脉病理的病人.

主要方法:

使用Mindray Resona 7超声波与Vflow软件进行矢量分析.
在内动脉静脉狭窄前后记录血流速度 (抽缩和放缩).
使用内置的矢量分析程序计算WSS和OSI.

主要成果:

与健康对照组相比,患有动脉动脉样硬化的患者表现出明显不同的WSS和OSI (p<0.001).
动脉硬化患者的平均动脉壁应力是动脉硬化患者的10倍以上 (0.05±0.01).
动荡指数在动脉样硬化患者中是7倍以上 (0.23±0.1).

结论:

壁切应力在内动脉狭窄水平上发生显著变化.
血液流速和变形值可以帮助识别血管壁狭窄的区域.
用于记录WSS的矢量流量映射为评估脑血管疾病中的动脉样硬化病变发展提供了一个有希望的新方法.

关键词:

动脉样硬化动脉样硬化血液流动速度血液的流动速度波动指数的波动指数是什么内动脉狭窄的内动脉狭窄.墙壁剪切压力压力压力

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