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铁化驱动的NIR酸染料在现场生成启用了零背景光成像和精确的外科瘤切除

Xiunan Xie1,2, Zhihao Lu1,2, Yuerui Kong1

  • 1Key Laboratory of Life-Organic Analysis of Shandong Province, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, 273165, P.R. China.

Angewandte Chemie (International ed. in English)
|November 25, 2025
PubMed
概括

这项研究引入了零背景光成像策略,以准确检测铁瘤中的基 (·OH). 这种方法提高了化学疗法引导瘤切除的诊断准确性.

关键词:
铁化是铁化的一种.基基 (·OH) 是一种基基.在现场合成.索拉费尼布 (Sorafenib) 是一种瘤切除术是指瘤的切除术.零背景光是零背景的光.

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Total Internal Reflection Fluorescence Microscopy01:05

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Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.