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Updated: Jan 10, 2026

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对C型莱克DC-SIGN的共价激活

Jonathan Lefèbre1,2,3, Maurice Besch1,2,3, Noémi Csorba4,5,6

  • 1Department of Pharmaceutical Sciences, University of Vienna, Josef-Holaubek-Platz 2, Vienna, 1090, Austria.

Angewandte Chemie (International ed. in English)
|November 25, 2025
PubMed
概括

研究人员开发了新的共价化合物来调节DC-SIGN功能,这是一个关键的免疫受体. 这些激活剂增强了连接体的结合,并为C型莱克调节提供了新的治疗策略.

关键词:
协同抑制的协同抑制.这是一个 DC-SIGN 信号.基于碎片的药物设计.葡萄糖生物学 葡萄糖生物学激活蛋白质的激活方式

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