EpiTrack:执行功能和记忆的评估中的直接和间接作用 - 系统性审查
Nazira Bekenova1, Alisher Aitkaliyev1,2, Balzhan Kassiyeva1
1Medical Center Hospital of President's Affairs Administration of the Republic of Kazakhstan, Astana, Kazakhstan.
Applied neuropsychology. Adult
|November 25, 2025
概括
在中认知障碍是常见的. 托皮拉显著恶化了认知,而神经刺激 (VNS) 与1-2种抗药物 (AED) 相结合显示出有意义的认知收益.
科学领域:
- 神经科学是一个神经科学.
- 临床神经学 临床神经学
- 药理学 药理学是指药理学的学科.
背景情况:
- 认知障碍经常与并发,影响患者的生活质量.
- 关于抗药物 (AED),迷走神经刺激 (VNS) 和手术如何影响执行功能和记忆的有限的比较数据存在.
研究的目的:
- 系统地审查和评估有关治疗对执行功能和记忆的影响的研究.
- 使用EpiTrack认知查工具评估认知变化.
主要方法:
- 一个系统的文献搜索发现了1008个出版物.
- 七项研究符合认知变化全文审查和分析的纳入标准.
主要成果:
- 佩拉曼奈尔和塞诺巴马特显示出中性认知特征 (中度认知障碍).
- 拉莫特里金和莱维西拉塞坦导致持续的严重功能障碍;托皮拉马特导致显著下降.
- 单独使用VNS疗法显示有轻微改善;使用1-2AED的VNS产生了有意义的益处,而使用3-4AED的VNS保持了严重的损伤.
结论:
- 准确的认知评估在管理中至关重要.
- 对于接受AED治疗的患者,建议每六个月监测认知功能.
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