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Sophie Hofer¹, Natalie Nussbaum¹, Peter Fischer¹

¹ETH Zurich, Institute of Food, Nutrition and Health, Schmelzbergstrasse 7, 8092 Zurich, Switzerland. peter.fischer@hest.ethz.ch.

|November 25, 2025

概括

在工程生物材料 (ELM) 中优化真菌生长需要精心设计基板. 这项研究确定了碳水化合物和蛋白质水平以及粘性弹性等关键因素,以增强3D应用的体活力.

科学领域:

生物技术是生物技术.
材料科学材料科学材料科学
菌类学菌类学是指菌类学.

背景情况:

工程生物材料 (ELM) 提供了新的应用.
菌发酵是ELM发展的一个关键方法.
基质设计对于ELM的真菌生长至关重要.

研究的目的:

为了评估各种基质上可食用的形成的真菌的生长活力.
为ELM应用确定影响真菌生长的关键非生物因素.
开发一个框架来选择和设计真菌生长基质.

主要方法:

评估了不同碳水化合物和蛋白质度的麦芽上七种真菌的辐射膨胀和菌根密度.
使用不同度的和凝剂 (,玉米粉, κ-carrageenan,细菌纤维素) 修改基质粘性.
泡为3D真菌生长提供了一个优化的基板.

主要成果:

碳水化合物度影响了辐射膨胀,中低水平的最佳速率,而较高度增加了菌体密度.
植物性蛋白质显著影响体厚度和扩张速度.
增加基质粘性弹性和优化3D泡增强了真菌的扩散.

结论:

基质成分 (碳水化合物,蛋白质) 和物理性质 (粘性弹性) 对于控制 ELM 中的真菌生长至关重要.
这项研究为ELM开发中食用真菌设计有效基质提供了基础.
优化的基质条件使得实践ELM应用中成功的3D真菌生长.

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