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一个偶然发现的上皮质血管内皮质瘤的病例

Sabrina B J Belfi1, Beata Bode-Lesniewska2,3, Ilhan Inci1,2,4

  • 1University of Nicosia Medical School, Makedonitissas Avenue, Nicosia CY-2417, Cyprus.

Journal of surgical case reports
|November 25, 2025
PubMed
概括

在接受非霍奇金治疗的患者中诊断出了一种罕见的上皮状血管内皮瘤 (EHE).

关键词:
甲状腺状的 血 末皮瘤.恶性多叶膜溢出 恶性多叶膜溢出胸部外科手术 胸部外科手术

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Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl hydroxylase and factor...