超声波胎儿体重估计百分位数在妊娠第二季度应谨慎解释
Ben Melamed1, Elad Mei-Dan2, Amir Aviram1
1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, Ontario, Canada.
概括
由于对错误的敏感性,胎儿体重 (EFW) 百分点的超声波估计在妊娠25周之前不太可靠. 腹周 (AC) 百分位为早期怀孕中诊断胎儿生长限制 (FGR) 提供了更可靠的衡量标准.
科学领域:
- 孕产妇和胎儿的医学
- 在产科中诊断成像.
- 胎儿成长评估 胎儿成长评估
背景情况:
- 准确的胎儿体重估计对于识别胎儿生长异常至关重要.
- 第二个三个月的超声波生物测量通常用于胎儿体重估计.
- 怀孕早期的限制可能会影响胎儿生长限制的及时诊断.
研究的目的:
- 划出第二个三个月的超声波胎儿体重 (EFW) 百分位数的局限性.
- 将EFW百分位数的准确性与单个胎儿生物识别指数进行比较.
- 建立一个妊娠年龄值,可靠诊断胎儿生长限制 (FGR).
主要方法:
- 使用1991年哈德洛克方法描述EFW限制的模拟.
- 来自第三级中心的单独怀孕队列 (2014-2023) 的分析.
- 通过ROC曲线,检测率和预测值评估的诊断准确性.
主要成果:
- 在怀孕25周之前,EFW百分位对轻微的约会或测量错误非常敏感.
- 在怀孕早期,腹周 (AC) 百分位表现出比EFW百分位更高的可靠性.
- 预测低出生体重 (<第10个百分位数) 的EFW百分位数的正预测值 (PPV) 在25周之前急剧下降.
结论:
- 在怀孕25周之前,超声波EFW百分位数的可靠性较低.
- 解释EFW百分位数在这个早期妊娠期需要谨慎.
- 在25周之前,AC百分位可能会成为评估胎儿成长的更强有力的指标.
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