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在患有多发性硬化症的妇女中,孕产妇和诊断延迟
Alexandra Balshi1, John P Dempsey2,3, Sachin Kumbar2,4
1Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave., Kirstein 215, Boston, MA, 02215, USA. alexandra_balshi@hms.harvard.edu.
Journal of neurology
|November 25, 2025
概括
与没有孩子的女性相比,患有多发性硬化症 (MS) 的母亲会经历更长的诊断延迟. 这种延迟在受雇和单身母亲中更为明显,突出了潜在的医疗保健准入差异.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 妇女健康 妇女健康
背景情况:
- 多发性硬化症 (MS) 是一种慢性神经疾病,主要影响生育年龄的女性.
- 在MS中诊断时间可以显著影响疾病管理和患者的结果.
- 父母身份是影响医疗保健寻求行为和诊断时间表的潜在因素.
研究的目的:
- 调查父母身份与多发性硬化症诊断时间之间的关联.
- 为了确定性别是否影响父母与MS诊断延迟之间的关系.
- 探索可能改变女性这种关联的特定人口因素 (就业,婚姻状况).
主要方法:
- 对多发性硬化症 (MS) 患者的诊断延迟的分析,按父母身份分层.
- 统计建模控制症状发作的年龄,疾病亚型,吸烟和健康的社会决定因素.
- 分层分析检查了就业和婚姻状况对妇女诊断延迟的影响.
主要成果:
- 与没有孩子的妇女相比,有孩子的妇女在MS诊断的时间显着更长 (β=1.28,p=0.001).
- 在男性中,没有观察到父母与诊断延迟之间的类似关联.
- 对于母亲来说,诊断延迟在受雇 (β=1.94,p=0.001) 和单身 (β=1.61,p=0.001) 妇女中更为明显.
结论:
- 母亲与女性多发性硬化症诊断的显著延迟有关.
- 诸如就业和单身婚姻状况等因素加剧了母亲的诊断延迟.
- 调查结果表明,母亲在获得医疗保健方面存在潜在的障碍或延迟,特别是那些面临额外社会经济压力的母亲.
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