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Updated: Jan 10, 2026

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铁素耐药性参与PTEN损失的前列腺癌进展

Yaoyao Jing1,2, Donghui Xing3, Zhigang Zhao4

  • 1Department of Day ward, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, 300060, China.

Discover oncology
|November 25, 2025
PubMed
概括

前列腺癌细胞中的酸酶和张素同源 (PTEN) 损失促进了对细胞死亡途径铁亡的抵抗力. 这种耐药性与增加的Glutathione peroxidase 4 (GPX4) 表达相关,这表明PTEN状态会影响铁灭症治疗的有效性.

关键词:
铁化是铁化的一种.在GPX4中使用GPX4.在这里,我们可以使用PTEN.前列腺癌是什么意思 前列腺癌是什么意思

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