相关实验视频

Updated: Jun 16, 2026

Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity
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Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity

Published on: November 11, 2017

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由重复磁刺激诱导的位置和频率依赖的突触可塑性的多尺度建模在金字塔神经元的树突中

Nicholas Hananeia1,2, Christian Ebner1,2,3, Christos Galanis4,5,6,7

  • 1Computer-Based Modelling in the Field of R Animal Protection, Faculty of Medicine, Justus Liebig University Giessen, Giessen, Germany.

PLoS computational biology
|November 25, 2025
PubMed
概括

一个新的建模框架模拟了神经元中重复性跨磁刺激 (rTMS) 诱导的突触可塑性. 该工具准确预测长期的潜在变化,有助于开发有效的rTMS协议.

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相关概念视频

Long-term Potentiation01:25

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when presynaptic neurons...