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Updated: Jan 10, 2026

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细胞巨乳病毒破坏了拉敏A/C,以控制微小管介导的核运动和细胞迁移

Jamil Mahmud1, Ipsita Nandi1, Dean J Procter1

  • 1Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.

Proceedings of the National Academy of Sciences of the United States of America
|November 25, 2025
PubMed
概括

人类细胞巨乳病毒 (HCMV) 操纵了拉胺A/C和SUN2,以控制核运动和细胞迁移. HCMV选择性地降低这些蛋白质的调节,使得乙化微管形成,这对于感染期间的细胞迁移至关重要.

关键词:
细胞巨乳病毒病毒.拉米兰 (Lamin) 拉米兰 (Lamin) 是一个微管是微管的组成部分.运动性 运动性 运动性一个核的核.

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