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用于口服固体剂量配方的脂友性API-离子液体 (API-IL) 和其固化产品的无隔离制造

Evangelia Tsolaki1, Entvin Mamo2, Rafel Lopez Rodriguez3

  • 1School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; SSPC, The Research Ireland Centre for Pharmaceuticals, School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; EPSRC-SFI Centre for Doctoral Training in Transformative Pharmaceutical Technologies, Ireland.

International journal of pharmaceutics
|November 25, 2025
PubMed
概括

连续的制药制造能够有效地合成和净化脂性API-离子液体 (API-ILs). 这种综合工艺,随后是喷雾封装,产生自由流动的粉末,用于口服固体剂型 (OSD).

关键词:
同心环状分离器是同心环状分离器.连续处理是连续处理.配方 配方 配方 是一个离子液体是一种离子液体.没有隔离的制造业液体液体提取方法 液体液体提取方法喷雾干燥 喷雾干燥

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