牙周病与中风风险之间的关联:系统性审查和元分析
Yuqing Zhang1, C E Bian1, Chaoran Yu1
1Department of Orthodontics, School of Stomatology, Capital Medical University, Beijing, China.
The journal of evidence-based dental practice
|November 25, 2025
概括
牙周病显著增加了72%的中风风险. 有效的牙科生物膜控制可以降低这种风险,强调口腔健康对脑血管预防的重要性.
科学领域:
- 心血管健康 心血管健康
- 口腔医学是指口腔医学.
- 流行病学 流行病学
背景情况:
- 牙周病是一种常见的炎症性疾病.
- 预防中风是一个主要的公共卫生问题.
- 牙周病和中风风险之间存在潜在的联系.
研究的目的:
- 评估牙周病与中风风险之间的关联.
- 综合来自多项关于这种关系的研究的证据.
主要方法:
- 按照PRISMA 2020指南进行系统审查和元分析.
- 搜索了主要的数据库 (PubMed,EMBASE,Scopus,科学网,科克兰图书馆) 到2024年12月.
- 使用纽卡斯尔-太华尺度评估研究质量,并将数据与随机效应模型合并.
主要成果:
- 包括36项研究,超过760万参与者.
- 牙周病与72.4%的中风风险增加有关 (OR: 1.724,95%CI: 1.481-2.008).
- 风险在不同人群和缺血性和出血性中风中都较高.
结论:
- 牙周病是中风的独立危险因素.
- 口腔卫生和牙生物膜控制可以减轻中风风险.
- 需要进一步的研究来阐明潜在的机制.
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