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Updated: Jan 10, 2026

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酸化合的TANGO1和Sec16A的自我调节维持了功能性的ER退出站点

Miharu Maeda1, Masashi Arakawa1, Masaki Wakabayashi2

  • 1Department of Biological Informatics and Experimental Therapeutics, Graduate School of Medicine, Hondo, Akita, Japan.

Nature communications
|November 25, 2025
PubMed
概括

保持TANGO1和Sec16A的正确酸化平衡对于ER退出部位 (ERES) 功能至关重要. 这种平衡由涉及FAM83A/CK1α和特定酸酶的反循环控制,确保适当的蛋白质分泌.

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