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Updated: Jan 10, 2026

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence
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来自老年个体的人类纤维细胞通过氧化应激引起的复制应激表现出染色体的不稳定性

Kailin Zhu1, Guan Chen1, Yueyi Ren1

  • 1Department of Molecular Oncology, Institute of Development, Aging and Cancer (IDAC), Tohoku University, Sendai, Miyagi, Japan.

npj aging
|November 25, 2025
PubMed
概括

衰老的人类细胞显示出由于氧化应激,线粒体功能障碍和复制应激增加的无体积,导致染色体不稳定性 (CIN). 抗氧化剂治疗逆转了这些与衰老相关的效应.

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