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Updated: Jan 10, 2026

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin
11:17

Stability and Structure of Bat Major Histocompatibility Complex Class I with Heterologous β2-Microglobulin

Published on: March 10, 2021

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在小鼠抗原呈现细胞中,主要基因相容性II类被修改为K63和K11连接的分支泛素链

Haiyin Liu1, Lauren Francis1, Laura F Dagley2,3

  • 1Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, 30 Flemington Rd, Parkville, VIC, 3010, Australia.

Scientific reports
|November 25, 2025
PubMed
概括

这项研究描述了免疫细胞中主要基因相容性II类 (MHC II) 分子上的无处不在链. 我们确定了分支的K11和K63泛素链,揭示了对适应性免疫调节的新见解.

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