相关实验视频

Updated: Jan 10, 2026

Cancer-Associated Fibroblasts from Mouse Mammary Tumors as Tools for Molecular and Computational Studies
09:01

Cancer-Associated Fibroblasts from Mouse Mammary Tumors as Tools for Molecular and Computational Studies

Published on: July 3, 2025

822

流体转录学揭示了LIF作为高瘤芽的关键效应因子三阴性乳腺癌

Pimchanok Phankeaw1, Suparada Khanaruksombat1,2, Warapan Numprasit3,4

  • 1Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, 10700, Thailand.

Scientific reports
|November 25, 2025
PubMed
概括

在三阴性乳腺癌 (TNBC) 中,高瘤芽 (TB) 与预后不佳相关. 纤维细胞激活蛋白 (FAP) - 阳性癌症相关纤维细胞 (CAF) 过度表达白血病抑制因子 (LIF),促进TNBC进展和免疫治疗耐药性.

关键词:
与癌症相关的纤维细胞细胞.纤维细胞激活蛋白是什么?白血病抑制因子抑制因子编程死亡联手 1 编程死亡联手 1三阴性乳腺癌是三阴性乳腺癌.瘤的芽正在发生.

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