在口腔癌中从手术到放射治疗后的营养监测:一项前性的纵向研究
Esther Sathiaraj1, Kamar Afshan2, Shivani Sharma2
1Department of Clinical Nutrition and Dietetics, HCG Cancer Hospitals, Bengaluru, India. esther.sathiaraj@gmail.com.
概括
在口腔癌治疗期间,营养状况显著下降,影响死亡率和再接收. 早期营养评估和干预对于改善患者的治疗结果至关重要.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 临床研究 临床研究
背景情况:
- 口腔癌的治疗往往涉及到多模式的方法,如手术和放射治疗.
- 营养状况是影响癌症治疗期间患者结果的关键因素.
研究的目的:
- 评估接受多式治疗的口腔癌患者的营养变化.
- 检查营养状况对死亡率和30天再接收的影响.
主要方法:
- 对100名口腔癌患者进行前性纵向研究.
- 营养评估包括BMI,BIA,HGS,血清白蛋白和五个时间点的饮食摄入量.
- 分析的结果:死亡率,30天再入院,粘膜炎严重程度,LOHS和放射治疗合规性.
主要成果:
- 在整个治疗过程中观察到体重,BMI,脂肪质量,肌肉质量和HGS的显著下降.
- 体重减轻>5%与严重的粘膜炎相关;低肌肉质量与较长的LOHS.
- 低albuminemia预测了更高的死亡率和30天的再入院.
结论:
- 口腔癌患者逐渐恶化的营养状况显著影响死亡率和再入院率.
- 危险患者的早期鉴定和结构化的营养监测是必不可少的.
- 方法论为未来的营养干预试验提供了一个框架.
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