与西德尼东南部B型肝炎延迟诊断相关的因素
Public health research & practice
|November 26, 2025
概括
三分之一因乙型肝炎病毒 (HBV) 感染而患有晚期肝病的人被诊断为晚期,错过了及时抗病毒治疗的机会. 需要制定战略来改善早期HBV诊断,特别是在女性和老年移民中.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 乙型肝炎病毒 (HBV) 感染是一个重大的全球健康问题.
- 慢性HBV可以导致严重的肝脏疾病,如不补偿性肝硬化 (DC) 和肝细胞癌 (HCC).
- 早期诊断HBV对于有效干预和预防晚期肝病至关重要.
研究的目的:
- 调查与B型肝炎病毒 (HBV) 晚期诊断相关的因素.
- 确定与延迟HBV检测有关的人口,地理和临床因素.
- 为改善早期HBV诊断和减少疾病负担的策略提供信息.
主要方法:
- 利用澳大利亚新南威尔士州HBV通知的基于人口的链接数据集.
- 包括住院数据和国家艾滋病毒登记册,以提供全面的患者信息.
- 晚期诊断定义为HBV通知在不补偿性肝硬化 (DC) 或肝细胞癌 (HCC) 诊断后两年内.
主要成果:
- 在2002年至2022年3月期间,有10,910人被报告感染HBV;296人 (3%) 患有DC或HCC.
- 晚期诊断发生在34%的晚期肝病患者中.
- 女性性别与晚期HBV诊断独立相关 (aOR 1.92). 对年龄较大的出生队伍,海外出生和酒精使用障碍的趋势.
结论:
- 晚期诊断HBV在晚期肝病患者中很常见,这阻碍了及时治疗.
- 需要有针对性的战略来加强早期HBV检测,特别是在妇女和来自西亚/南亚的移民中.
- 局部化数据和数据链接对于理解和解决HBV负担以及推进消除工作至关重要.
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