前列腺癌的脑转移与神经症状作为第一个迹象:一个病例报告
Chuanjian Chen1,2, Chunhao Mo1, Shaolong Zhang1
1Department of Urology, Gansu Province Clinical Research Center for urinary system disease, Lanzhou University Second Hospital, Lanzhou, People's Republic of China.
概括
这一案例突出显示了一种罕见的前列腺癌脑转移病例,发生在细胞/细胞上区域. 内分泌疗法有效地减少了原发性和转移性瘤,副作用最小.
科学领域:
- 在瘤学瘤学.
- 神经学 神经学
- 内分泌学 在内分泌学.
背景情况:
- 前列腺癌通常会转移到骨和淋巴结.
- 内脏和中枢神经系统的转移很少发生.
- 来自前列腺癌的细胞和细胞上脑转移异常罕见.
研究的目的:
- 报告一个罕见的前列腺癌与大脑转移的病例.
- 讨论细胞/细胞上前列腺癌转移的管理.
- 在这种情况下,评估内分泌治疗的疗效.
主要方法:
- 一个80岁的男性患有双眼视和尿路症状的病例介绍.
- 大脑MRI显示细胞/细胞上病变.
- 增加的前列腺特异性抗原 (PSA) 水平和通过尿道切除的前列腺切除证实了前列腺腺癌.
主要成果:
- 这名患者被诊断为转移性激素敏感前列腺癌 (mHSPC).
- 图像检查证实了细胞上转移性病变.
- 内分泌疗法导致原发性和转移性病变的显著减少.
结论:
- 由前列腺癌引起的大脑转移是一种罕见的临床表现.
- 基于基剥夺疗法 (ADT) 的内分泌疗法显示出显著的疗效.
- 治疗导致瘤负担减少,没有显著的不良影响.
相关概念视频
02:30Metastasis
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
02:30Metastasis
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
01:19Multiple Sclerosis l: Introduction
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...