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Updated: Jan 10, 2026

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在临床试验期间同时进行剂量修改的情况下,终点暴露-反应分析

Rui Zhong1,2, Yanguang Cao1

  • 1Division of Pharmacotherapy and Experimental Therapeutics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Clinical pharmacology and therapeutics
|November 26, 2025
PubMed
概括

由于不良事件 (AE) 的剂量修改,传统的暴露-反应分析可能会误导. 为AE驱动的剂量修改进行调整可以提高准确性,这对于可靠的药物开发和剂量选择至关重要.

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