在TCR结合后,T细胞的辅助刺激和抑制信号二次调节LAT凝聚物核化倾向

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Updated: Jan 10, 2026

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins
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A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins

Published on: March 22, 2012

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Saehyun Choi1, Sungi Kim1, Jessica Tijham1

  • 1Department of Chemistry, University of California, Berkeley; Berkeley, CA 94720, USA.

bioRxiv : the preprint server for biology
|November 26, 2025
PubMed
概括

造价刺激信号 (CD80/CD86) 在T细胞受体 (TCR) 激活后加速激活T细胞激活链接器 (LAT) 凝聚物形成. 抑制PD-L1具有轻微的对抗作用,影响T细胞信号动态.

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