线

Azusa Terasaki1, Alexis T Weiner1, Yuhao Tan2

  • 1Department of Pathology, Stanford University, Stanford, CA 94305, USA.

概括

癌细胞通过与免疫细胞共享线粒体来维持瘤生长,并重新编程它们以抑制抗瘤反应. 破坏这种线粒体交换会损害瘤的进展和免疫力.

相关概念视频

The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
7.6K