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相关概念视频

Longitudinal Studies01:26

Longitudinal Studies

454
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
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Longitudinal Research02:20

Longitudinal Research

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Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
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Brain Imaging01:14

Brain Imaging

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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
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Three Developmental Domains01:29

Three Developmental Domains

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Human development is typically examined across three main domains: physical, cognitive, and socio-emotional. These domains represent the significant areas of change and continuity throughout the lifespan, from infancy to late adulthood.
Physical Development
Physical processes, also known as maturation, encompass the biological changes that occur across an individual's life. These changes begin with genetic inheritance and continue through various stages, including growth in height and weight,...
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Information Processing Approach01:30

Information Processing Approach

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The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
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A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
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一个开放的,完全处理的,纵向数据资源来研究大脑发育和跨诊断执行功能.

Brooke L Sevchik1,2,3, Golia Shafiei1,2,3, Kristin Murtha1,2,3,4

  • 1Penn Lifespan Informatics and Neuroimaging Center, University of Pennsylvania, PA, USA.

bioRxiv : the preprint server for biology
|November 26, 2025
PubMed
概括
此摘要是机器生成的。

本研究介绍了青少年发育中的宾夕法尼亚州长度执行功能 (Penn LEAD) 数据集,这是了解青少年执行功能 (EF) 发展和精神病理学的宝贵资源.

关键词:
更多关于 ADHD ADHD 的文章青少年时期 青春期认知 认知是一种认知.发展发展发展 发展发展执行职能 执行职能 执行职能纵向的 纵向的 纵向的这就是为什么MRI是MRI.神经成像是一种神经成像.精神错乱是一种精神病.

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科学领域:

  • 神经科学是一个神经科学.
  • 发展心理学 发展心理学
  • 精神病学是一个精神病学.

背景情况:

  • 执行功能 (EF) 在青春期经历了快速发展.
  • EF 缺陷是与各种精神病理相关的跨诊断症状.
  • 青春期是EF发展和精神健康状况出现的关键时期.

研究的目的:

  • 介绍宾夕法尼亚州长度执行功能在青少年发展 (宾夕法尼亚州领导) 研究数据集.
  • 促进青春期执行功能发展的跨诊断研究.
  • 为研究EF和精神病理学提供一个全面的多模式数据资源.

主要方法:

  • 从132名 (8-16岁) 个体进行了纵向数据收集.
  • 包括典型的发展年轻人,注意力缺陷多动症 (ADHD) 和精神病谱群.
  • 多模式数据采集:结构MRI,扩散MRI,fMRI (n-back任务,休息状态) 和动脉旋转标记MRI,以及认知和临床表型.

主要成果:

  • 宾夕法尼亚州LEAD数据集包括225次成像会议.
  • 数据包括多样化的参与者群体,使比较分析成为可能.
  • 所有原始和处理的数据,包括质量控制建议,都在OpenNeuro上公开提供.

结论:

  • 宾夕法尼亚大学LEAD数据集是一个重要的,分析准备的资源,用于推进青少年执行功能研究.
  • 公开共享的数据将加速对EF发展及其与精神病理学的关系的跨诊断研究.
  • 本资源支持对精神疾病中神经发育轨迹的更深入的理解.