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突变和ACE2诱导的Allosteric网络重新连接在delta和OmicronSARS-CoV-2尖端蛋白中

Mandira Dutta1, Gregory A Voth1

  • 1Department of Chemistry, Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, IL 60637.

bioRxiv : the preprint server for biology
|November 26, 2025
PubMed
概括

这项研究揭示了SARS-CoV-2变种Delta和Omicron如何在它们的尖端蛋白中使用不同的全性传播途径,影响病毒的进入和传染性. 了解这些网络有助于设计适应性抗病毒策略来对抗不断变化的变种.

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