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Updated: Jan 10, 2026

Production of Adeno-Associated Virus Vectors in Cell Stacks for Preclinical Studies in Large Animal Models
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使用电荷检测质谱仪对AAV制造过程进行端到端的表征

Lohra M Young1, Benjamin E Draper1, Martin F Jarrold1

  • 1Megadalton Solutions, Inc., Bloomington, IN 47404, USA.

Molecular therapy. Methods & clinical development
|November 26, 2025
PubMed
概括

电荷检测质谱 (CD-MS) 在整个制造过程中有效监测复合腺相关病毒 (rAAV) 的质量. 这种技术为从收获到最终药物物质的rAAV生产提供了可重复的定量洞察力.

关键词:
腺相关病毒的病毒.检测电荷的质谱学质谱学.基因治疗的基因疗法百分比 百分比 百分比 百分比 百分比 百分比过程优化优化过程优化过程扩大规模,扩大规模.纯度纯度纯度纯度纯度纯度纯度

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