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Updated: Jan 10, 2026

Validation of Therapeutic Agent Conjugation to Polyvinyl Alcohol-Coated Medical Devices
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通过口服输送西马格卢提德和蒂尔泽帕提德,使用来自牛奶的小细胞外囊泡

Yuefei Zhang1,2,3, Jianyi Han1,2,3, Wei Wu1,2,3

  • 1Research Center for Industries of the Future and Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences Westlake University Hangzhou Zhejiang China.

Journal of extracellular biology
|November 26, 2025
PubMed
概括

小细胞外囊泡 (sEVs) 为口服输送提供了一个有前途的解决方案,克服胃肠道障碍. 这项研究表明,牛奶衍生的sEVs成功地输送GLP-1RAs,如semaglutide和tirzepatide,降低糖尿病小鼠的血糖.

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