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Updated: Jan 10, 2026

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis
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Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis

Published on: June 27, 2020

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在肺大细胞神经内分泌癌中基于转录因子的亚型分配

Yin P Hung1, Komson Wannasai1,2, Catherine B Meador3

  • 1Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Histopathology
|November 26, 2025
PubMed
概括

基于转录因子的亚型化有助于区分肺大细胞神经内分泌癌 (LCNEC) 和小细胞肺癌 (SCLC). 在LCNEC中,YAP1和HNF4A的表达与大细胞形态相关.

关键词:
在ASCL1中,这就是HNF4A.这是一个神经D1D1的过程.在POU2F3F3中.一个YAP1一个YAP1大细胞神经内分泌癌细胞瘤

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