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Updated: Jan 10, 2026

Live-Cell Förster Resonance Energy Transfer Imaging of Metabolically Regulated Akt Activation Dynamics in HepG2 Cells
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托利德通过PRKN介导的ACSL1的全方位化阻碍HK2细胞中高葡萄糖诱导的细胞功能

Jiangsong Jia1, Wen-Ming Zhao1, Xin Wang1

  • 1Department of Pharmacy, Henan Provincial People's Hospital; People's Hospital of Zhengzhou University; People's Hospital of Henan University, Zhengzhou, Henan, 450003, China.

The Journal of endocrinology
|November 26, 2025
PubMed
概括

ptolide (TP) 通过上调parkin (PRKN) 来保护糖尿病脏病,这会降解乙基-CoA合成酶长链家族成员1 (ACSL1),减轻管损伤和铁亡.

关键词:
长链阿基尔-甲合成酶家族成员1糖尿病脏病 糖尿病脏病铁性化 (ferroptosis) 是一种停车场可以停车.三托利化物是什么

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