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相关概念视频

Phylogenetic Trees03:21

Phylogenetic Trees

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Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.
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Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

6.8K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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Phylogeny01:23

Phylogeny

56.6K
Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.
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Survival Tree01:19

Survival Tree

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Survival trees are a non-parametric method used in survival analysis to model the relationship between a set of covariates and the time until an event of interest occurs, often referred to as the "time-to-event" or "survival time." This method is particularly useful when dealing with censored data, where the event has not occurred for some individuals by the end of the study period, or when the exact time of the event is unknown.
 Building a Survival Tree
Constructing a...
374
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

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The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
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Gene Duplication and Divergence02:37

Gene Duplication and Divergence

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The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
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相关实验视频

Updated: Jan 10, 2026

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin
08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

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种类树枝长度估计尽管不完整的血统排序,重复和损失.

Yasamin Tabatabaee1, Chao Zhang2, Shayesteh Arasti3

  • 1Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

Genome biology and evolution
|November 26, 2025
PubMed
概括
此摘要是机器生成的。

CASTLES-Pro准确地估计了物种树枝的长度,即使基因重复和损失. 这种新方法改进了现有的多位点遗传学分析工具.

关键词:
树枝长度估计 树枝长度估计基因重复和基因丢失横向基因转移是指水平基因转移.不完整的血统排序 不完整的血统排序人类基因组学是什么?种类 树木 树木 种类 树木

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A Practical Guide to Phylogenetics for Nonexperts
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A Concoction Pipeline for Generating Molecular Operational Taxonomic Units (MOTUs) Among Riparian and Aquatic Beetles
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相关实验视频

Last Updated: Jan 10, 2026

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08:57

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

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A Practical Guide to Phylogenetics for Nonexperts
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A Practical Guide to Phylogenetics for Nonexperts

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A Concoction Pipeline for Generating Molecular Operational Taxonomic Units (MOTUs) Among Riparian and Aquatic Beetles
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A Concoction Pipeline for Generating Molecular Operational Taxonomic Units (MOTUs) Among Riparian and Aquatic Beetles

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科学领域:

  • 人类遗传学 是一个学科.
  • 进化生物学 进化生物学
  • 生物信息学是一种生物信息学.

背景情况:

  • 遗传学分支的长度对于进化分析至关重要.
  • 来自不完整的血统排序,重复和损失的基因树异质性使物种树枝长度估计变得复杂.
  • 现有的方法不足以解决多副本基因家族树.

研究的目的:

  • 介绍CASTLES-Pro,一种用于估计物种树枝长度的算法.
  • 为了考虑到基因重复/损失和不完整的血统排序在分支长度估计中.
  • 改进现有的方法,如单复制和多复制基因树的CASTLES.

主要方法:

  • 开发了CASTLES-Pro算法. 开发了CASTLES-Pro算法. 开发了CASTLES-Pro算法. 开发了CASTLES-Pro算法. 开发了CASTLES-Pro算法.
  • 利用模拟研究来评估性能.
  • 将CASTLES-Pro与其他方法进行比较,包括连接.

主要成果:

  • CASTLES-Pro的准确性比现有替代品更高.
  • 该算法减轻了连接中常见的终端分支长度过高估计.
  • CASTLES-Pro显示了相对稳健的水平基因转移.

结论:

  • CASTLES-Pro为物种树枝长度估计提供了一个强大的解决方案.
  • 该方法有效地处理基因复制,丢失和不完整的血统分类.
  • CASTLES-Pro代表了多个位置的遗传学分析的重大进步.