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Updated: Jun 22, 2026

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在高风险神经母细胞瘤中对诱导化疗的组织学反应

Monica Pomaville1, Pei-Chi Kao2,3, Antonio Perez-Atayde2,4

  • 1Department of Pediatric Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Cancer medicine
|November 26, 2025
PubMed
概括

神经母细胞瘤瘤在化疗后显示出显著的组织学变化,变得更加差异化. 然而,这些变化并不能预测患者的生存结果.

关键词:
组织学 组织学神经母细胞瘤的神经母细胞瘤预后 预后 预后风险分层的风险分层.

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...