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Updated: May 3, 2026

The Fabrication and Operation of a Continuous Flow, Micro-Electroporation System with Permeabilization Detection
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使用电场梯度的球体的电穿孔:研究强度依赖透性的工具

Théo Le Berre1, Julien Marchalot1, Guilhem Rival2

  • 1Ecole Centrale de Lyon, INSA Lyon, Universite Claude Bernard Lyon 1, CNRS, Ampère, UMR5005, 69130 Ecully, France. theo.le-berre@ec-lyon.fr.

Lab on a chip
|November 26, 2025
PubMed
概括

电穿孔 (EPN) 使用电场使细胞膜具有透性. 一个新的微设备允许在3D癌症球体上系统地研究EPN,揭示异质的透模式.

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相关概念视频

Calculation of Electric Flux01:25

Calculation of Electric Flux

Consider the electric field of an oppositely charged, parallel-plate system and an imaginary box between those plates. Let the bottom face of the box be ABCD, and the top face be FGHK. The electric field between the plates is uniform and points from the positive plate toward the negative plate. The calculation of this field's flux through the box's various faces shows that the net flux through the box is zero. Why does the flux cancel out here?
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Finding Electric Potential From Electric Field01:13

Finding Electric Potential From Electric Field

For a system of charges, it is easy to calculate the system's potential because potential is a scalar quantity. However, in some instances where calculating the electric field is more straightforward than finding the potential, the electric field is used to calculate the system's potential. For a positive charge, the electric field is radially outward, and the potential is positive at any finite distance from the positive charge. In such an electric field, the motion away from the...
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Determining Electric Field From Electric Potential01:12

Determining Electric Field From Electric Potential

The electric field and electric potential are related to each other. If the electric field at various points in the region of interest is known, it can be used to calculate the electric potential difference between any two points. Similarly, if the electric potential is known for various points, then it is possible to calculate the electric field.
In general, regardless of whether the electric field is uniform, it points in the direction of decreasing potential because the force on a positive...
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Induced Electric Fields: Applications01:27

Induced Electric Fields: Applications

An important distinction exists between the electric field induced by a changing magnetic field and the electrostatic field produced by a fixed charge distribution. Specifically, the induced electric field is nonconservative because it does not work in moving a charge over a closed path. In contrast, the electrostatic field is conservative and does no net work over a closed path. Hence, electric potential can be associated with the electrostatic field but not the induced field. The following...
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Electric Field of Parallel Conducting Plates01:16

Electric Field of Parallel Conducting Plates

Gauss' law relates the electric flux through a closed surface to the net charge enclosed by that surface. Gauss's law can be applied to find the electric field and the charge enclosed in a region depending on its charge distribution.
Consider a cross-section of a thin, infinite conducting plate having a positive charge. For such a large thin plate, as the thickness of the plate tends to zero, the positive charges lie on the plate's two large faces. Without an external electric field, the...
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Electrostatic Boundary Conditions01:16

Electrostatic Boundary Conditions

Consider an external electric field propagating through a homogeneous medium. When the electric field crosses the surface boundary of the medium, it undergoes a discontinuity. The electric field can be resolved into normal and tangential components. The amount by which the field changes at any boundary is given by the difference between the field components above and below the surface boundary.
The surface integral of an electric field is given by Gauss's law in integral form and is related to...
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