可重新安排对老年乳腺癌患者疼痛管理实践的影响

Chan Shen^1,2,3, Mohammad Ikram¹, Shouhao Zhou^2,3

¹Department of Surgery, College of Medicine, The Pennsylvania State University, Hershey, PA 17033, USA.

Current oncology (Toronto, Ont.)

|November 26, 2025

概括

可的重新安排 (日程表III至II) 减少了其在老年乳腺癌患者的使用,将处方转向其他阿片类药物. 需要进一步研究疼痛管理结果.

科学领域:

在瘤学瘤学.
药理学药理学是指药理学的学科.
公共卫生政策公共卫生政策

背景情况:

阿片类药物处方法规对患者护理有重大影响.
在2014年重新安排 (表III至表II) 引入了更严格的控制.
这些变化对乳腺癌患者疼痛管理的影响以前尚不清楚.

研究的目的:

评估可重新安排对疼痛管理策略的影响.
评估早期乳腺癌老年妇女处方阿片类药物模式的变化.
分析可,非可类阿片类药物,NSAIDs和抗抑郁药物的使用趋势后重新安排.

主要方法:

使用SEER-Medicare数据 (2011-2019) 的回顾性队列研究.
鉴定了52,792名年龄≥66岁的妇女,患有早期乳腺癌.
评估趋势并使用多变量逻辑回归来分析处方变化.

主要成果:

可使用量从55%降至40%;非可类阿片类药物使用量从43%增加到50%.
确认了可使用的显著减少 (AOR:0.81) 和非可类阿片类药物使用的增加 (AOR:1.25).
可剂量下降,而非可类阿片类药物剂量保持稳定;NSAID和抗抑郁药的使用没有显著变化.

结论:

可重新安排显著改变了老年乳腺癌患者的阿片类药物处方.
显著的转变发生了从可到替代阿片类止痛药.
需要进行进一步的研究,以评估这些在癌症疼痛管理中的处方转变的临床适当性和结果.

关键词:

在SEER-Medicare数据中.乳腺癌乳腺癌乳腺癌可的重新安排.阿片类药物和非阿片类药物药理疗.疼痛管理疼痛管理

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