美国菌菌病导致的死亡:对死亡证明上报告的病例分析,2018-2023年
Huiqiao Fan1, Fariba Donovan2, Belinda Lovelace3
1Department of Pharmacy Practice, School of Pharmacy, University of Connecticut, Storrs, CT 06269, USA.
Journal of fungi (Basel, Switzerland)
|November 26, 2025
概括
从2019年到2023年,菌菌病死亡人数增加,老年男性和某些种族的死亡率更高. 许多死亡人数列出了其他主要原因,突出了需要更好地诊断和治疗菌杆菌菌病的需要.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 目前关于菌菌病 (山谷热) 死亡率的数据有限.
- 了解当前的死亡率和风险因素对于公共卫生干预至关重要.
研究的目的:
- 评估可归因于菌菌的死亡率,并使用最近的美国数据确定人口和地理风险因素.
- 评估死亡率的趋势和死亡证书中将菌菌菌病列为主要原因的比例.
主要方法:
- 对美国国家生命统计系统死亡证明数据的分析,从2018年到2023年.
- 使用ICD-10代码B38.x.x.识别菌菌病的死亡情况.
- 根据年龄调整的死亡率 (AAMR) 和人口统计学和并发病因素的相对风险的计算.
主要成果:
- 鉴定了1760例可归因于菌菌的死亡病例 (AAMR = 0.75/100,000).
- 在55-74岁的个人,男性,以及美洲印第安人/阿拉斯加原住民和西班牙裔人口中观察到更高的AAMR.
- 从2019年开始,AAMR增加了,亚利桑那州显示的最高率. 在只有40.5%的病例中,皮性菌病是主要原因.
- 糖尿病,COVID-19和艾滋病毒等并发症在菌菌病死亡中更为频繁.
结论:
- 型菌病的死亡率与既定的人口和地理因素密切相关,观察到的趋势越来越大.
- 主要原因编码的比例很低,这表明人们对菌菌病作为死亡原因的认可不足.
- 对于高风险个人和人群,建议提高临床意识,早期诊断和及时的抗真菌治疗.
更多相关视频
10:06Efficient Method for Imaging Murine Lungs that Preserves Spatial Dynamics of Fungal Spores in the Airways
Published on: December 13, 2024
793
05:08Application of I TASSER, trRosetta, UCSF Chimera, HADDOCK server, and HEX loria for De Novo and In Silico Design of Proteins
Published on: July 8, 2025
909
相关概念视频
01:08Prevalence and Incidence
1.5K
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.5K
01:21Causality in Epidemiology
1.5K
Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
1.5K
01:28Fungal Phylum Microsporidia
395
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
395
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
5.3K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
5.3K
01:20COPD: Pathogenesis and Clinical Features
1.7K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.7K
01:22Chronic Obstructive Pulmonary Disease
2.2K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
2.2K