关于HPV疫苗接种的全球观点:巴西经验的成就,挑战和教训
Antonio Braga1,2,3, Caroline Alves de Oliveira Martins2, Gabriela Paiva1,2
1Department of Gynecology and Obstetrics, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro 22240-003, RJ, Brazil.
人类乳头瘤病毒 (HPV) 疫苗接种显著减少了宫癌. 成功的全球战略需要基于学校的一致交付,适应性政策,如单剂量方案,以及打击错误信息,以改善疫苗覆盖率.
科学领域:
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
- 预防癌症 预防癌症
背景情况:
- 预防性HPV疫苗接种是全球预防宫癌的关键.
- 低收入和中等收入国家在HPV疫苗实施,覆盖率和犹方面面临挑战.
- 本综述审查了全球和巴西的HPV疫苗接种计划,并指出了取得的成就,挑战和未来的战略.
研究的目的:
- 审查全球和巴西的HPV疫苗接种计划.
- 为未来的HPV疫苗接种策略突出成就,陷和教训.
- 评估HPV疫苗对宫癌预防的影响.
主要方法:
- 对同行评审文献进行叙事审查.
- 分析来自国际和巴西卫生组织的官方报告.
- 专注于计划性表现,覆盖趋势和疫苗接受度.
主要成果:
- 高收入国家通过以学校为基础的计划显著降低了HPV的流行率.
- 巴西的HPV疫苗接种计划最初覆盖率很高,随后由于错误信息和交付问题而下降.
- 单剂量HPV疫苗方案在印度和非洲国家的成本效益和可行性方面显示出希望.
结论:
- 接种HPV疫苗可以大大降低全球宫癌发病率.
- 持续的影响需要普遍获得,一致的学校教育,适应性政策 (例如单剂量) 和有效的沟通来应对错误信息.
- 巴西的经验为实现世卫组织90-70-90目标提供了宝贵的教训.
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