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Updated: Jun 17, 2026

High-throughput Screening for Small-molecule Modulators of Inward Rectifier Potassium Channels
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使用TRP通道功能化查发现肺下降草药和生物活性成分的研究

Bin Yu1, Jiaye Tian1, Zewen Wang1

  • 1Key Laboratory of TCM-Information Engineer of State Administration of TCM, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.

Naunyn-Schmiedeberg's archives of pharmacology
|November 26, 2025
PubMed
概括

这项研究表明,具有肺下降性质的传统中国草药,如拉法尼精液 (RS) 和Descurainiae Semen Lepidii Semen (DSLS),激活TRPM8通道. 这些草药为开发针对TRP通道的呼吸治疗方法提供了新的途径.

关键词:
信号传递的.肺部下降的草药 肺部下降的草药分子对接是分子对接.网络药理学 网络药理学在 TRP 道功能化选中.在 TRPM8 频道上播放.

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