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Updated: Jan 6, 2026

Generation of Cancer Cell Clones to Visualize Telomeric Repeat-containing RNA TERRA Expressed from a Single Telomere in Living Cells
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在慢性髓性白血病细胞系中逆转诱导的端粒结构重塑:来自TeloView®的见解3D核结构分析

Fábio Morato de Oliveira1, Isabela Dias Cruvinel1, Bruno Machado Rezende Ferreira1

  • 1Laboratory of Human and Medical Genetics, Federal University of Jataí, Jataí 75801-615, Goiás, Brazil.

Current issues in molecular biology
|November 26, 2025
PubMed
概括

逆转触发了亡,并通过抑制 Aurora 激酶来重塑慢性髓性白血病 (CML) 细胞中的端粒. 这项研究揭示了它对基因组稳定性和核组织的双重作用,表明了治疗潜力.

关键词:
在TeloView®上使用.极光化酶 (Aurora Kinase) 是一种激素.慢性骨髓性白血病 慢性骨髓性白血病基因组的不稳定性这是一个反向的反向.端粒是什么意思 端粒是什么意思

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