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Updated: Jan 10, 2026

Generating Transgenic Plants with Single-copy Insertions Using BIBAC-GW Binary Vector
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Generating Transgenic Plants with Single-copy Insertions Using BIBAC-GW Binary Vector

Published on: March 28, 2018

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PGDD 2.0:植物基因组复制数据库,更新了内容和工具

Ankush Sharma1,2, John E Bowers1,2, Tae-Ho Lee3

  • 1Plant Genome Mapping Laboratory, University of Georgia, Athens, GA 30602, United States.

Nucleic acids research
|November 26, 2025
PubMed
概括

通过整合120多个端粒对端粒基因组组合,PGDD 2.0增强了植物比较基因组学. 这个更新的数据库有助于高精度地理解植物基因组进化,多重化和基因重复事件.

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The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
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While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
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The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
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Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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