母亲的不良童年经历和围产期结果:一个回顾性的初始队列研究
Amanda Troëng1, Jessica Dolk1, Marie-Therese Vinnars2
1Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
PloS one
|November 26, 2025
概括
母亲暴露于多次不良童年经历 (ACE) 显著增加了不良围产期结果的风险,包括紧急剖腹产和孕前. 识别和支持高ACE的妇女对于改善母亲和婴儿健康至关重要.
科学领域:
- 围产期健康 围产期健康
- 公共卫生 公共卫生
- 心理社会妇产科 心理社会妇产科
背景情况:
- 不利的童年经历 (ACE) 与负面的成年健康结果有关.
- 有限的研究存在于累积ACEs对围产期健康的影响.
- 这项研究调查了母体ACE和围产期结局之间的关联.
研究的目的:
- 检查母亲暴露于多种ACE和不良周产期结局之间的关系.
- 为了确定累积ACEs对分娩并发症和怀孕期间母亲健康的影响.
主要方法:
- 一项针对瑞典1,253名妇女 (2012-2013) 的队列研究,使用产前医疗保健计划数据.
- 问卷评估了ACE,分娩方式和分娩并发症.
- 使用调整为混因子的顺序逻辑回归分析.
主要成果:
- 具有≥4个ACE类别的女性对不良结果的调整几率比率最高.
- 在紧急剖腹产 (aOR 2.02),产后出血 (aOR 3.54),孕前 (aOR 4.21) 和抗生素使用 (aOR 3.14) 中发现了重要的关联.
- 观察到剂量-反应关系,增加ACE与较差的结果相关.
结论:
- 多个ACE与不良周产期结局的增加率有关.
- 孕产妇卫生服务应确定高ACE的妇女,以提供有针对性的支持.
- 早期干预可以帮助减轻怀孕期间与ACE相关的风险.
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