在小鼠中,来自不同物种的PrP的受管制共表达会影响子菌株的复制和宿主范围特性

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Joseph P DeFranco1, Jifeng Bian1, Sehun Kim1

  • 1Prion Research Center, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523.

Proceedings of the National Academy of Sciences of the United States of America
|November 26, 2025
PubMed
概括

特定物种的蛋白 (PrPC) 变异影响病. 同表达的旁观者PrPC可以抑制或增强子复制,并在物种间传播期间改变菌株特性.

关键词:
慢性消耗性疾病慢性消耗性疾病传染性宿主范围的范围.神经退行性疾病的神经退行性疾病子是一种子.菌株 菌株 菌株 菌株

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