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Updated: Jan 10, 2026

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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CTCF-RNA相互作用编排细胞特异性染色蛋白循环组织

Kimberly Lucero1,2, Sungwook Han2,3,4, Pin-Yao Huang2

  • 1Department of Cell Biology and Regenerative Medicine, New York University Langone Medical Center, New York, NY, USA.

Science advances
|November 26, 2025
PubMed
概括

与RNA的CCCCTC结合因子 (CTCF) 相互作用对于维持细胞特异性基因组结构至关重要. 破坏CTCF的行为

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