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在重症患者的连续置换治疗期间发生的不良事件:一项回顾性队列研究

Heitor de Melo Keller¹, Priscilla Caroliny de Oliveira¹, Aline de Sá Mendes²

¹Faculdade Israelita de Ciências da Saude Albert Einstein, Sao Paulo, Brazil.

Australian critical care : official journal of the Confederation of Australian Critical Care Nurses

|November 26, 2025

概括

在重症患者中,持续的置换疗法 (CRRT) 与不良事件 (AE) 有关. 血管活性药物,机械通风,多种设备,男性性别,较高的SAPS 3分数和年龄较大增加AE风险.

科学领域:

关键护理医学关键护理医学
腎臟病學 (nephrology) 是一種醫學專業.
患者安全患者安全

背景情况:

连续置换疗法 (CRRT) 是严重损伤患者的重要治疗方法.
在CRRT期间发生的不良事件 (AEs) 可以使患者的治疗和结果复杂化.
识别CRRT相关副作用的风险因素对于提高患者安全至关重要.

研究的目的:

在重症患者的连续脏替代疗法 (CRRT) 中确定不良事件 (AEs) 的独立风险因素.
在这个脆弱人群中为预防AE提供有针对性的干预信息.

主要方法:

对1361名接受CRRT的重症患者进行了回顾性队列研究.
收集的数据包括人口统计,临床变量和CRRT相关的副作用.
使用负二项式回归分析来确定AE的独立风险因素.

主要成果:

167名患者 (12.2%) 经历了意外事件,主要是中度事件和压力损伤.
副作用最常发生在CRRT的前六天内.
增加AE发病率的独立风险因素包括血管活性药物使用,超过4种侵入性设备,机械通风,男性性别,较高的SAPS 3分数和年龄较大.

结论:

在重症患者中,CRRT相关的副作用与特定的临床因素有关.
血管活性药物使用,机械通风,高侵入性设备负担,男性性别,高SAPS 3和年龄较大是显著的危险因素.
积极的监测和有针对性的干预措施对于提高CRRT期间的患者安全至关重要.

关键词:

持续的替代疗法持续的替代疗法设备和用品以及供应.重症监护病房的重症监护病房是重症监护病房.护理护理护理患者安全患者安全脏替代疗法是指脏替代疗法.

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